Daniel Larremore

Daniel B. Larremore

About Me

I finished a PhD in Applied Mathematics from the University of Colorado Boulder in 2012, advised by Juan G. Restrepo, after which I spent three years as a postdoctoral fellow at the Harvard T.H. Chan School of Public Health studying the genetic epidemiology of malaria in the Center for Communicable Disease Dynamics. I then joined the Santa Fe Institute as an Omidyar Fellow until 2017, when I joined the faculty at the University of Colorado Boulder in the Department of Computer Science and the BioFrontiers Institute.

Research Interests

  • Malaria's antigenic variation and evolution - The var genes of the malaria parasite P. falciparum evolve according to complicated and unknown rules, with selective pressures at multiple scales both within hosts and between hosts. I create and use mathematical tools to understand the structural and evolutionary constraints on var gene evolution, and their relationships with parasite virulence, population structure, and epidemiology.
  • Networks and theory - The processes that generate complex networks leave hints about themselves in the patterns of edges, and the relationships between those patterns and vertex metadata. I work on mathematical descriptions of graph ensembles, inference of community structures, vertex ordering or ranking, and using metadata to better understand network formation.
  • The scientific ecosystem - The scientific method of hypothesis, experiment, and conclusion poorly describes modern scientific discovery and productivity. Instead, science is done by people who play various social roles in the ecosystem of science. I investigate faculty hiring, productivity patterns, scientific careers, and the dynamics of discovery through large-scale data collection and modeling.

Outside the Lab

I lean in to Boulder stereotypes by climbing, mountain biking, running, and skiing. Boulder is a beautiful place to live, so I try to get outside a lot. I like to read, usually in a cycle consisting of nonfiction, literature, and science fiction. When I have time, I like to make art, typically sculpture with paper. If I had to do another job outside of science, I think I’d like to be a writer.